Subhojit Roy, MD, PhD. Principal Investigator, Fundraiser, Cheerleader, Neuropathologist and elite e-mail forwarder
I, Subhojit (various pronunciations exist - "soob - oh! - jeet" being the most popular) started life in a small copper mining town in the state of Rajasthan, India, where my father was an engineer. I then went to medical school in Calcutta, India, with every intention to pursue a career in general Medicine. However a series of highly improbable misadventures led me to abandon this predictable path and enter the US (long story). Despite never having held a pipette in medical school (didn't even really know what a pipette was), I decided to do a PhD in neuronal cell biology with Mark Black at Temple (I cannot think of any good reason for this other than my expiring visa....). Anyway, my thesis work helped resolve a key controversy at that time, and instilled a desire of "finding new things". After a rather intense training-period of residency/fellowship and post-doctoral research in neurodegenerative neuropathology/cell biology with Virginia Lee and John Trojanowski at the ever-vibrant University of Pennsylvania), the Roy Lab was founded in 2008. See my scientific ancestry at Neurotree
A static cell is a dead cell. My broad interest is to explore movement within cells, specifically within neurons - mechanisms that convey, deposit and retain cargoes in axons, dendrites and synapses. Towards this, we are interested in physiologic neuronal transport/trafficking, and also potential abnormalities in these processes in neurodegenerative diseases like Alzheimer's and Parkinson's disease. I am also board-certified in anatomic- and neuro- pathology.
A static cell is a dead cell. My broad interest is to explore movement within cells, specifically within neurons - mechanisms that convey, deposit and retain cargoes in axons, dendrites and synapses. Towards this, we are interested in physiologic neuronal transport/trafficking, and also potential abnormalities in these processes in neurodegenerative diseases like Alzheimer's and Parkinson's disease. I am also board-certified in anatomic- and neuro- pathology.
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Mailing address:
Subhojit Roy, MD, PhD Professor, Depts. of Pathology and Neuroscience UW Medical foundation Professor Director, Neuropathology Core, Wisconsin Alzheimer's center Rm 5533, Wisconsin Institute for Medical Research (WIMR II) Mail Drop ID: 8550 1111 Highland Avenue Madison, WI 53705 email: roy27[at]wisc[dot]edu Jichao Sun ("JC"), PhD. Postdoctoral fellow
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My life as a Neuropathologist
A severely atrophic brain ravaged by Alzheimer's disease Click for a slide presentation. If needed, click here for the accompanying audio (will open in separate windows, ignore first 1:20 of audio)
See Dr. Roy's profile at UW Stem Cell and Regenerative Center: https://stemcells.wisc.edu/node/1576 Pankaj Dubey, PhD. Postdoctoral fellow
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Jonathan Loi ("Mr. Singh"). PhD student (jjloi at wisc dot edu)
Jon's publications from Roy lab (started Fall 2016):
1. Ganguly A, Tang Y, Wang L, Ladt K, Loi J, Dargent D, Leterrier C, and Roy S. (2015) A dynamic formin-dependent deep F-actin network in axons. Journal of Cell Biology, July 27 issue; 210(3).
2. Ganguly A, Han X, Das U, Wang L, Loi J, Sun J, Gitler D, Caillol G, Leterrier C, Yates JR 3rd, Roy S. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin. J Cell Biol. 2017 May 30
1. Ganguly A, Tang Y, Wang L, Ladt K, Loi J, Dargent D, Leterrier C, and Roy S. (2015) A dynamic formin-dependent deep F-actin network in axons. Journal of Cell Biology, July 27 issue; 210(3).
2. Ganguly A, Han X, Das U, Wang L, Loi J, Sun J, Gitler D, Caillol G, Leterrier C, Yates JR 3rd, Roy S. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin. J Cell Biol. 2017 May 30
