Subhojit Roy, MD, PhD. Principal Investigator, Fundraiser, Cheerleader, Neuropathologist and elite e-mail forwarder
"Subhojit" has various pronunciations ("soob - oh! - jeet" being the most popular). I started life in a small copper mining town in the state of Rajasthan, India, where my father was an engineer. I then went to medical school in Calcutta, India, with every intention to pursue a career in general Medicine. However a series of highly improbable misadventures led me to abandon this predictable path and enter the US (long story). Despite never having held a pipette in medical school (didn't even really know what a pipette was), I decided to do a PhD in neuronal cell biology with Mark Black at Temple. My PhD thesis work helped resolve a key controversy at that time, and instilled a desire of "finding new things". After a rather intense training-period of residency/fellowship and post-doctoral research in neurodegenerative neuropathology/cell biology with Virginia Lee at University of Pennsylvania, the Roy Lab was founded in 2008. Places I've lived: Rajasthan, Kolkata, Philadelphia, San Diego, Madison WI. See my scientific ancestry at Neurotree. Blog about my career path: https://crosstalk.cell.com/blog/there-is-no-right-career-path-a-perspective-from-an-immigrant-physician-scientist and podcast (RARECAST) on gene therapy in neurodegenerative diseases: globalgenes.org/rare-cast/episode-323/ A static cell is a dead cell. The broad interest of my laboratory is to explore movement in neurons – trafficking mechanisms that convey, deposit, and retain cargoes in axons, dendrites and synapses. A related interest is to manipulate trafficking-pathways for therapeutics in neurodegenerative diseases; particularly gene- and CRISPR- based therapies. |
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Mailing address:
Subhojit Roy, MD, PhD Professor, Depts. of Pathology and Neuroscience Rm 2124, BRF-2 9500 Gilman Drive #0626 La Jolla, CA 92093-0626 email: sroy@ucsd.edu Brent Aulston, PhD. Postdoctoral fellow (on Neurodegeneration training grant)
Joined Roy lab July 2019, working on a CRISPR based gene therapy for Alzheimer's disease.
PhD: Gordon Glazner lab, U of Mannitoba Rohan Sharma, PhD. Postdoctoral fellow
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Leonardo (Leo) Parra, PhD. Postdoctoral fellow (APDA postdoctoral fellow)
Joined Roy lab Aug 2019, PhD: Erik Jorgensen lab, Utah. Working on alpha synuclein pathophysiology.
1. Ganguly A*, Sharma R*, Boyer NP, Wernert F, Phan S, Boassa D, Parra L, Das U, Caillol G, Han X, Yates JR 3rd, Ellisman MH, Leterrier C, Roy S. Clathrin packets move in slow axonal transport and deliver functional payloads to synapses. Neuron. 2021 Sep 15;109(18):2884-2901.e7. Kristen Branes, Research Assistant and Lab Manager
Joined September 2019.
- 2020 Parkinson’s Foundation Summer Student Fellow, project: Conserving Physiological Parameters While Attenuating Alpha-Synuclein Induced Pathology Via CRISPR/Cas9. Nick Boyer, PhD. Postdoctoral fellow
.Joins the Roy lab Sept 2020 (also in the middle of pandemic). PhD: Stephanie Gupton, UNC. Working on neuronal cytoskeleton.
Veronica Cerada, PhD. Postdoctoral fellow
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