CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S*. Nat Commun. 2019 Jan 3;10(1):53. doi: 10.1038/s41467-018-07971-8. PMID: 30604771; PMCID: PMC6318289.
https://pubmed.ncbi.nlm.nih.gov/30604771/

Efficient in vivo neuronal genome editing in the mouse brain using nanocapsules containing CRISPR-Cas9 ribonucleoproteins. Metzger JM, Wang Y, Neuman SS, Snow KJ, Murray SA, Lutz CM, Bondarenko V, Felton J, Gimse K, Xie R, Li D, Zhao Y, Flowers MT, Simmons HA, Roy, S, Saha K,
Levine JE, Emborg ME, Gong S. 
Biomaterials. 2023 Feb;293:121959. doi: 10.1016/j.biomaterials.2022.121959. Epub 2022 Dec 13. PMID: 36527789; PMCID: PMC9868115.

Review: 
Sun J, Roy S*. Gene-based therapies for neurodegenerative diseases. Nat Neurosci. 2021 Mar;24(3):297-311. doi: 10.1038/s41593-020-00778-1. Epub 2021 Feb 1. PMID: 33526943; PMCID: PMC8394447.
https://pubmed.ncbi.nlm.nih.gov/33526943/