Scott DA, Tabarean I, Tang Y, Cartier A, Masliah E, Roy S*. A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. J Neurosci. 2010 Jun 16;30(24):8083-95. doi: 10.1523/JNEUROSCI.1091-10.2010. PMID: 20554859; PMCID: PMC2901533.
https://pubmed.ncbi.nlm.nih.gov/20554859/
Tang Y, Das U, Scott DA, Roy S*. The slow axonal transport of alpha-synuclein--mechanistic commonalities amongst diverse cytosolic cargoes. Cytoskeleton. 2012 Jul;69(7):506-13. doi: 10.1002/cm.21019. Epub 2012 Mar 2. PMID: 22344896; PMCID: PMC3376189.
https://pubmed.ncbi.nlm.nih.gov/22344896/
Scott D, Roy S*. α-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis. J Neurosci. 2012 Jul 25;32(30):10129-35. doi: 10.1523/JNEUROSCI.0535-12.2012. PMID: 22836248; PMCID: PMC3426499.
https://pubmed.ncbi.nlm.nih.gov/22836248/
Wang L, Das U, Scott DA, Tang Y, McLean PJ, Roy S*. α-synuclein multimers cluster synaptic vesicles and attenuate recycling. Curr Biol. 2014 Oct 6;24(19):2319-26. doi: 10.1016/j.cub.2014.08.027. Epub 2014 Sep 25. PMID: 25264250; PMCID: PMC4190006.
https://pubmed.ncbi.nlm.nih.gov/25264250/
Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen LA, Masliah E, Gage FH*. Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology. J Neurosci. 2017 Feb 15;37(7):1675-1684. doi: 10.1523/JNEUROSCI.3047-16.2016. Epub 2016 Dec 30. PMID: 28039370; PMCID: PMC5320602.
https://pubmed.ncbi.nlm.nih.gov/28039370/
Atias M, Tevet Y, Sun J, Stavsky A, Tal S, Kahn J, Roy S*, Gitler D*. Synapsins regulate α-synuclein functions. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11116-11118. doi: 10.1073/pnas.1903054116. Epub 2019 May 20. PMID: 31110014; PMCID: PMC6561288. (* co-corresponding)
https://pubmed.ncbi.nlm.nih.gov/31110014/
Sun J, Wang L, Bao H, Premi S, Das U, Chapman ER, Roy S*. Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11113-11115. doi: 10.1073/pnas.1903049116. Epub 2019 May 20. PMID: 31110017; PMCID: PMC6561242.
https://pubmed.ncbi.nlm.nih.gov/31110017/
Parra-Rivas LA, Madhivanan K, Aulston BD, Wang L, Prakashchand DD, Boyer NP, Saia-Cereda VM, Branes-Guerrero K, Pizzo DP, Bagchi P, Sundar VS, Tang Y, Das U,
Scott DA, Rangamani P, Ogawa Y, Subhojit Roy. Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein
interactions and synaptic function. Neuron. 2023 Dec 20;111(24):4006-4023, PMID: 38128479.
https://pubmed.ncbi.nlm.nih.gov/38128479/
Synapsin E-domain is essential for a-synuclein function. Alexandra Stavsky, Leonardo A. Parra-Rivas, Shani Tal, Kayalvizhi Madhivanan, Subhojit Roy* and Daniel Gitler* (* co-corresponding). eLife, 2023
https://pubmed.ncbi.nlm.nih.gov/38713200/
Reviews/Commentaries:
Roy S*. The paradoxical cell biology of alpha-Synuclein. Results Probl Cell Differ. 2009;48:159-72. doi: 10.1007/400_2009_23. PMID: 19582404.
https://pubmed.ncbi.nlm.nih.gov/19582404/
Roy S*. Synuclein and dopamine: the Bonnie and Clyde of Parkinson's disease. Nat Neurosci. 2017 Oct 26;20(11):1514-1515. doi: 10.1038/nn.4660. PMID: 29073642.
https://pubmed.ncbi.nlm.nih.gov/29073642/
https://pubmed.ncbi.nlm.nih.gov/20554859/
Tang Y, Das U, Scott DA, Roy S*. The slow axonal transport of alpha-synuclein--mechanistic commonalities amongst diverse cytosolic cargoes. Cytoskeleton. 2012 Jul;69(7):506-13. doi: 10.1002/cm.21019. Epub 2012 Mar 2. PMID: 22344896; PMCID: PMC3376189.
https://pubmed.ncbi.nlm.nih.gov/22344896/
Scott D, Roy S*. α-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis. J Neurosci. 2012 Jul 25;32(30):10129-35. doi: 10.1523/JNEUROSCI.0535-12.2012. PMID: 22836248; PMCID: PMC3426499.
https://pubmed.ncbi.nlm.nih.gov/22836248/
Wang L, Das U, Scott DA, Tang Y, McLean PJ, Roy S*. α-synuclein multimers cluster synaptic vesicles and attenuate recycling. Curr Biol. 2014 Oct 6;24(19):2319-26. doi: 10.1016/j.cub.2014.08.027. Epub 2014 Sep 25. PMID: 25264250; PMCID: PMC4190006.
https://pubmed.ncbi.nlm.nih.gov/25264250/
Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen LA, Masliah E, Gage FH*. Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology. J Neurosci. 2017 Feb 15;37(7):1675-1684. doi: 10.1523/JNEUROSCI.3047-16.2016. Epub 2016 Dec 30. PMID: 28039370; PMCID: PMC5320602.
https://pubmed.ncbi.nlm.nih.gov/28039370/
Atias M, Tevet Y, Sun J, Stavsky A, Tal S, Kahn J, Roy S*, Gitler D*. Synapsins regulate α-synuclein functions. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11116-11118. doi: 10.1073/pnas.1903054116. Epub 2019 May 20. PMID: 31110014; PMCID: PMC6561288. (* co-corresponding)
https://pubmed.ncbi.nlm.nih.gov/31110014/
Sun J, Wang L, Bao H, Premi S, Das U, Chapman ER, Roy S*. Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11113-11115. doi: 10.1073/pnas.1903049116. Epub 2019 May 20. PMID: 31110017; PMCID: PMC6561242.
https://pubmed.ncbi.nlm.nih.gov/31110017/
Parra-Rivas LA, Madhivanan K, Aulston BD, Wang L, Prakashchand DD, Boyer NP, Saia-Cereda VM, Branes-Guerrero K, Pizzo DP, Bagchi P, Sundar VS, Tang Y, Das U,
Scott DA, Rangamani P, Ogawa Y, Subhojit Roy. Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein
interactions and synaptic function. Neuron. 2023 Dec 20;111(24):4006-4023, PMID: 38128479.
https://pubmed.ncbi.nlm.nih.gov/38128479/
Synapsin E-domain is essential for a-synuclein function. Alexandra Stavsky, Leonardo A. Parra-Rivas, Shani Tal, Kayalvizhi Madhivanan, Subhojit Roy* and Daniel Gitler* (* co-corresponding). eLife, 2023
https://pubmed.ncbi.nlm.nih.gov/38713200/
Reviews/Commentaries:
Roy S*. The paradoxical cell biology of alpha-Synuclein. Results Probl Cell Differ. 2009;48:159-72. doi: 10.1007/400_2009_23. PMID: 19582404.
https://pubmed.ncbi.nlm.nih.gov/19582404/
Roy S*. Synuclein and dopamine: the Bonnie and Clyde of Parkinson's disease. Nat Neurosci. 2017 Oct 26;20(11):1514-1515. doi: 10.1038/nn.4660. PMID: 29073642.
https://pubmed.ncbi.nlm.nih.gov/29073642/